Involvement of metabotropic glutamate receptor 5, AKT/PI3K Signaling and NF-κB pathway in methamphetamine-mediated increase in IL-6 and IL-8 expression in astrocytes

<p>Abstract</p> <p>Methamphetamine (MA) is one of the commonly used illicit drugs and the central nervous system toxicity of MA is well documented. The mechanisms contributing to this toxicity have not been fully elucidated. In this study, we investigated the effect of MA on the ex...

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Bibliographic Details
Main Authors: Shah Ankit, Silverstein Peter S, Singh Dhirendra P, Kumar Anil
Format: Article
Language:English
Published: BMC 2012-03-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:http://www.jneuroinflammation.com/content/9/1/52