Rapamycin Generates Graft-Homing Murine Suppressor CD8 T Cells That Confer Donor-Specific Graft Protection
It has been reported that rapamycin (RPM) can induce de novo conversion of the conventional CD4 + Foxp3-T cells into CD4 + Foxp3 + regulatory T cells (iTregs) in transplantation setting. It is not clear whether RPM can similarly generate suppressor CD8 + T cells to facilitate graft acceptance. In th...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2011-12-01
|
| Series: | Cell Transplantation |
| Online Access: | https://doi.org/10.3727/096368911X566244 |