Golgi-independent routes support protein disulfide isomerase externalization in vascular smooth muscle cells

Extracellular pools of intracellular molecular chaperones are increasingly evident. The peri/epicellular(pec) pool of the endoplasmic reticulum redox chaperone protein disulfide isomerase-A1(PDI) is involved in thrombosis and vascular remodeling, while PDI externalization routes remain elusive. In e...

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Bibliographic Details
Main Authors: Thaís L.S. Araujo, Carolina G. Fernandes, Francisco R.M. Laurindo
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231717302550