Modeling Human Prostate Cancer Metastasis in Mice via Resection of Subcutaneous Allografts

Modeling Human Prostate Cancer Metastasis in Mice via Resection of Subcutaneous Allografts

The 5-year survival rate for patients diagnosed with distant metastatic prostate cancer in the United States is 30.6%. Therefore, there is a great need to develop in vivo model systems to study prostate cancer metastasis and to test potential therapeutics. Most murine prostate cancer metastatic mode...

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Bibliographic Details
Main Authors: Lauren B. Peiffer, Jessica Hicks, Rebecca Y. Sosa, Angelo M. De Marzo, Karen S. Sfanos, Janielle P. Maynard
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Oncology
Subjects:
prostate cancer1
metastasis2
Myc-CaP3
allograft4
mouse model5
resection6
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.877536/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.877536/full

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