Quantitative trait loci affecting atherosclerosis at the aortic root identified in an intercross between DBA2J and 129S6 apolipoprotein E-null mice.

Quantitative trait loci affecting atherosclerosis at the aortic root identified in an intercross between DBA2J and 129S6 apolipoprotein E-null mice.

Apolipoprotein E-null mice on a DBA/2J genetic background (DBA-apoE) are highly susceptible to atherosclerosis in the aortic root area compared with those on a 129S6 background (129-apoE). To explore atherosclerosis-responsible genetic regions, we performed a quantitative trait locus (QTL) analysis...

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Bibliographic Details
Main Authors: Yukako Kayashima, Hirofumi Tomita, Svetlana Zhilicheva, Shinja Kim, Hyung-Suk Kim, Brian J Bennett, Nobuyo Maeda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0088274&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0088274&type=printable

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