The Preliminary Study of Effects of Tolfenamic Acid on Cell Proliferation, Cell Apoptosis, and Intracellular Collagen Deposition in Keloid Fibroblasts In Vitro

Keloid scarring is a fibroproliferative disorder due to the accumulation of collagen type I. Tolfenamic acid (TA), a nonsteroidal anti-inflammatory drug, has been found to potentially affect the synthesis of collagen in rats. In this preliminary study, we aimed to test the effects of TA on cell prol...

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Bibliographic Details
Main Authors: Dan Yi, Ji Bihl, Mackenzie S. Newman, Yanfang Chen, Richard Simman
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Dermatology Research and Practice
Online Access:http://dx.doi.org/10.1155/2014/736957