Synthesis, antiplasmodial activity and in silico molecular docking study of pinocembrin and its analogs

Synthesis, antiplasmodial activity and in silico molecular docking study of pinocembrin and its analogs

Abstract Background Malaria remains the major health problem responsible for many mortality and morbidity in developing countries. Because of the development of resistance by Plasmodium species, searching effective antimalarial agents becomes increasingly important. Pinocembrin is a flavanone previo...

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Bibliographic Details
Main Authors: Yadessa Melaku, Melat Solomon, Rajalakshmanan Eswaramoorthy, Uwe Beifuss, Vladimir Ondrus, Yalemtsehay Mekonnen
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Chemistry
Subjects:
Catalytic hydrogenation
Claisen-Schmidt Condensation
Malaria
Plasmodium berghei
Pinocembrin
Chloropinocembrin
Online Access:https://doi.org/10.1186/s13065-022-00831-z

Internet

https://doi.org/10.1186/s13065-022-00831-z

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