Phospho-Mimetic Mutation at Ser602 Inactivates Human TRPA1 Channel

Phospho-Mimetic Mutation at Ser602 Inactivates Human TRPA1 Channel

The Transient Receptor Potential Ankyrin 1 (TRPA1) channel is an integrative molecular sensor for detecting environmental irritant compounds, endogenous proalgesic and inflammatory agents, pressure, and temperature. Different post-translational modifications participate in the discrimination of the...

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Bibliographic Details
Main Authors: Kristyna Barvikova, Ivan Barvik, Viktor Sinica, Lucie Zimova, Viktorie Vlachova
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
transient receptor potential ankyrin 1
TRP channel
protein kinases
phosphomimetic
mutagenesis
phosphorylation
Online Access:https://www.mdpi.com/1422-0067/21/21/7995

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https://www.mdpi.com/1422-0067/21/21/7995

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