The clinical relevance of broad mutational screening of myeloproliferative neoplasms at diagnosis

The clinical relevance of broad mutational screening of myeloproliferative neoplasms at diagnosis

IntroductionMyeloproliferative neoplasm (MPN) is a heterogenous group of hematological malignancies including polycythemia vera (PV), essential thrombocythemia (ET) and primary myelofibrosis (PMF). JAK2V617F is the most frequent driver mutation in all three entities, but in PMF and ET mutations in C...

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Bibliographic Details
Main Authors: Helna Pettersson, Jenni Adamsson, Peter Johansson, Staffan Nilsson, Lars Palmqvist, Björn Andréasson, Julia Asp
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Oncology
Subjects:
MPN
JAK2
CALR
MPL
germline
mutation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1190305/full

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https://www.frontiersin.org/articles/10.3389/fonc.2023.1190305/full

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