Synthesis and Anti-Hyperlipidemic Evaluation of N‑(Benzoylphenyl)-5-fluoro-1H-indole-2-carboxamide Derivatives in Triton WR-1339-Induced Hyperlipidemic Rats

Synthesis and Anti-Hyperlipidemic Evaluation of N‑(Benzoylphenyl)-5-fluoro-1H-indole-2-carboxamide Derivatives in Triton WR-1339-Induced Hyperlipidemic Rats

The lipid-lowering activity of a series of novel N-(benzoylphenyl)-5-fluoro-1H-indole-2-carboxamide derivatives has been studied in Triton WR-1339-induced hyperlipidemia in rats. The test animals were divided into four groups: control, hyperlipidemic, compound + 4% DMSO [C1: N-(2-benzoylphenyl)-5-fl...

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Bibliographic Details
Main Authors: Tariq Al-Qirim, Moyad Shahwan, Waseem El-Huneidi, Yusuf Al-Hiari, Ghassan Shattat, Ghassan Abu Sheikha, Rania Al-Qirim
Format: Article
Language:English
Published: MDPI AG 2010-08-01
Series:Molecules
Subjects:
Triton WR-1339-induced hyperlipidemic rats
N-(benzoylphenyl)-5-fluoro-1H-indole-2-carboxamides
high-density lipoprotein-cholesterol
triglycerides
hypolipidemic activity
Online Access:http://www.mdpi.com/1420-3049/15/9/5840/

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http://www.mdpi.com/1420-3049/15/9/5840/

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