Herpesvirus lytic infection-induced mitophagy via viral interferon regulatory factor 1

ABSTRACTViral control of mitochondria via mitophagy has a dampening effect on mitochondrion-mediated innate immune responses. We previously found that human herpesvirus 8 (HHV-8) could activate mitophagy via its lytic gene product vIRF-1 (viral interferon regulatory factor 1). Mechanistically, we pr...

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Bibliographic Details
Main Authors: Mai Tram Vo, Young Bong Choi
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Autophagy Reports
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/27694127.2023.2281135