Role of COX-2/PGE2 signaling pathway in the apoptosis of rat ovarian granulosa cells induced by MEHP

Role of COX-2/PGE2 signaling pathway in the apoptosis of rat ovarian granulosa cells induced by MEHP

Objective: MEHP, as the metabolite of DEHP, is a widely used environmental endocrine disruptor. Ovarian granulosa cells participate in maintaining the function of ovary and COX2/PGE2 pathway may regulate the function of granulosa cells. We aimed to explore how COX-2/PGE2 pathway affects cell apoptos...

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Bibliographic Details
Main Authors:	Xu Li, Ying Zhu, Tianyang Zhao, Xueting Zhang, Honghao Qian, Jia Wang, Xiaohan Miao, Liting Zhou, Na Li, Lin Ye
Format:	Article
Language:	English
Published:	Elsevier 2023-04-01
Series:	Ecotoxicology and Environmental Safety
Subjects:	MEHP Ovarian granulosa cell Apoptosis COX-2/PGE2
Online Access:	http://www.sciencedirect.com/science/article/pii/S014765132300221X

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