Experimental and Modeling Study of Drug Release from HPMC-Based Erodible Oral Thin Films

Experimental and Modeling Study of Drug Release from HPMC-Based Erodible Oral Thin Films

In this work hydroxypropyl methylcellulose (HPMC) fast-dissolving thin films for oral administration are investigated. Furosemide (Class IV of the Biopharmaceutical Classification System) has been used as a model drug for in vitro release tests using three different set-ups: the Franz cell, the mill...

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Bibliographic Details
Main Authors: Alessandra Adrover, Gabriele Varani, Patrizia Paolicelli, Stefania Petralito, Laura Di Muzio, Maria Antonietta Casadei, Ingunn Tho
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Pharmaceutics
Subjects:
erodible thin films
HPMC
cyclodextrins
furosemide
Franz cell
USP II
millifluidic flow-through device
erosion
Online Access:https://www.mdpi.com/1999-4923/10/4/222

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https://www.mdpi.com/1999-4923/10/4/222

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