Auranofin, a thioredoxin reductase inhibitor, causes platelet death through calcium overload
Platelets are central to normal hemostasis and must be tightly controlled to prevent thrombosis. However, drug treatments that also affect platelets could lead to unwanted side effects on hemostasis or thrombosis. In this study, the effect of auranofin on platelets was tested. Auranofin, a gold-base...
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Format: | Article |
Language: | English |
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Taylor & Francis Group
2019-01-01
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Series: | Platelets |
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Online Access: | http://dx.doi.org/10.1080/09537104.2017.1378809 |