Auranofin, a thioredoxin reductase inhibitor, causes platelet death through calcium overload

Platelets are central to normal hemostasis and must be tightly controlled to prevent thrombosis. However, drug treatments that also affect platelets could lead to unwanted side effects on hemostasis or thrombosis. In this study, the effect of auranofin on platelets was tested. Auranofin, a gold-base...

Full description

Bibliographic Details
Main Author: Matthew T. Harper
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Platelets
Subjects:
Online Access:http://dx.doi.org/10.1080/09537104.2017.1378809