Tumor spectrum, tumor latency and tumor incidence of the Pten-deficient mice.
Pten functionally acts as a tumor suppressor gene. Lately, tissue-specific ablation of Pten gene in mice has elucidated the role of Pten in different tumor progression models. However, a temporally controlled Pten loss in all adult tissues to examine susceptibility of various tissues to Pten-deficie...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-11-01
|
| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC2077932?pdf=render |