In vivo function and evolution of the eutherian-specific pluripotency marker UTF1.

Embryogenesis in placental mammals is sustained by exquisite interplay between the embryo proper and placenta. UTF1 is a developmentally regulated gene expressed in both cell lineages. Here, we analyzed the consequence of loss of the UTF1 gene during mouse development. We found that homozygous UTF1...

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Auteurs principaux: Masazumi Nishimoto, Miyuki Katano, Toshiyuki Yamagishi, Tomoaki Hishida, Masayoshi Kamon, Ayumu Suzuki, Masataka Hirasaki, Yoko Nabeshima, Yo-ichi Nabeshima, Yukako Katsura, Yoko Satta, Janine E Deakin, Jennifer A Marshall Graves, Yoko Kuroki, Ryuichi Ono, Fumitoshi Ishino, Masatsugu Ema, Satoru Takahashi, Hidemasa Kato, Akihiko Okuda
Format: Article
Langue:English
Publié: Public Library of Science (PLoS) 2013-01-01
Collection:PLoS ONE
Accès en ligne:http://europepmc.org/articles/PMC3706607?pdf=render