Mechanisms of 5-HT receptor antagonists in the regulation of fibrosis in a 3D human liver spheroid model
Abstract Non-alcoholic steatohepatitis (NASH) is a major health problem leading to liver fibrosis and hepatocellular carcinoma, among other diseases, and for which there is still no approved drug treatment. Previous studies in animal models and in LX-2 cells have indicated a role for serotonin (5-HT...
| المؤلفون الرئيسيون: | , , , |
|---|---|
| التنسيق: | مقال |
| اللغة: | English |
| منشور في: |
Nature Portfolio
2024-01-01
|
| سلاسل: | Scientific Reports |
| الوصول للمادة أونلاين: | https://doi.org/10.1038/s41598-023-49240-9 |