Longitudinal Assessment of Lung Cancer Progression in Mice Using the Sodium Iodide Symporter Reporter Gene and SPECT/CT Imaging.

Lung cancer has the highest mortality rate of any tissue-specific cancer in both men and women. Research continues to investigate novel drugs and therapies to mitigate poor treatment efficacy, but the lack of a good descriptive lung cancer animal model for preclinical drug evaluation remains an obst...

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Bibliographic Details
Main Authors: Dominique N Price, Amber A McBride, Martina Anton, Donna F Kusewitt, Jeffrey P Norenberg, Debra A MacKenzie, Todd A Thompson, Pavan Muttil
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5201271?pdf=render