Interaction of peripheral CD4+CD25+CD127− Tregs with prolactin in HCV hepatocellular carcinoma: oncogenic or immunogenic mechanisms

Interaction of peripheral CD4+CD25+CD127− Tregs with prolactin in HCV hepatocellular carcinoma: oncogenic or immunogenic mechanisms

Abstract Background and objective There is little and conflicting data about the peripheral CD4+CD25+CD127− Tregs in patients with hepatocellular carcinoma (HCC) of various etiologies. The expressed membrane-bound transforming growth factor (mTGF-β1) on these Tregs is a marker of their suppressive f...

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Bibliographic Details
Main Authors: Mona Abd El-Rahman Abu El-Makarem, Douaa Mohammed Sayed, Ragaa Abdelshaheed Matta, Mahmoud Ragab Mohamed, Manal Ameer Abd El-Malak, Nehal Ibrahim Abbas
Format: Article
Language:English
Published: SpringerOpen 2023-04-01
Series:Egyptian Liver Journal
Subjects:
HCV-related hepatocellular carcinoma
T-regulatory cells
Prolactin
Peripheral CD4 + CD25 + CD127- Tregs
Membranous TGF-β1
Online Access:https://doi.org/10.1186/s43066-023-00250-2

Internet

https://doi.org/10.1186/s43066-023-00250-2

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