Oncogenic signaling inhibits c-FLIPL expression and its non-apoptotic function during ECM-detachment

Abstract Inhibition of programmed cell death pathways is frequently observed in cancer cells where it functions to facilitate tumor progression. However, some proteins involved in the regulation of cell death function dichotomously to both promote and inhibit cell death depending on the cellular con...

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Bibliographic Details
Main Authors: Matyas Abel Tsegaye, Jianping He, Kyle McGeehan, Ireland M. Murphy, Mati Nemera, Zachary T. Schafer
Format: Article
Language:English
Published: Nature Portfolio 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-97715-4