Tumor Acidity as Evolutionary Spite
Most cancer cells shift their metabolic pathway from a metabolism reflecting the Pasteur-effect into one reflecting the Warburg-effect. This shift creates an acidic microenvironment around the tumor and becomes the driving force for a positive carcinogenesis feedback loop. As a consequence of tumor...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2011-01-01
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Series: | Cancers |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6694/3/1/408/ |