Plasmacytoid Dendritic Cell Impairment in Metastatic Melanoma by Lactic Acidosis

Plasmacytoid Dendritic Cell Impairment in Metastatic Melanoma by Lactic Acidosis

The introduction of targeted therapies and immunotherapies has significantly improved the outcome of metastatic melanoma (MM) patients. These approaches rely on immune functions for their anti-melanoma response. Plasmacytoid dendritic cells (pDCs) exhibit anti-tumor function by production of effecto...

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Bibliographic Details
Main Authors: Matilde Monti, Raffaella Vescovi, Francesca Consoli, Davide Farina, Daniele Moratto, Alfredo Berruti, Claudia Specchia, William Vermi
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cancers
Subjects:
plasmacytoid dendritic cells
melanoma
lactate dehydrogenase
TLR
interferon
CXCL10
Online Access:https://www.mdpi.com/2072-6694/12/8/2085

Internet

https://www.mdpi.com/2072-6694/12/8/2085

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