Central 5-HT2A receptors modulate the vagal bradycardia in response to activation of the von Bezold-Jarisch reflex in anesthetized rats

Central 5-HT2A receptors modulate the vagal bradycardia in response to activation of the von Bezold-Jarisch reflex in anesthetized rats

Activation of 5-hydroxytryptamine (5-HT) 5-HT1A, 5-HT2C, 5-HT3, and 5-HT7 receptors modulates the excitability of cardiac vagal motoneurones, but the precise role of 5-HT2A/2B receptors in these phenomena is unclear. We report here the effects of intracisternal (ic) administration of selective 5-HT2...

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Bibliographic Details
Main Authors: H.A. Futuro Neto, S.M. Macedo, N.F. Silva, A.M. Cabral, J.G.P. Pires
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2011-03-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
5-HT2 receptors
R-96544
Reflex bradycardia
SB-204741
Vagal motoneurons
von Bezold-Jarisch reflex
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000300008

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000300008

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