The role of cancer predisposition syndrome in children and adolescents with very rare tumours

The role of cancer predisposition syndrome in children and adolescents with very rare tumours

Germline predisposing pathogenic variants (GPVs) are present in approximately 8–10 % of children with all cancer types. Very rare tumours (VRTs) represent many different diseases, defined with an annual incidence < 2 / 1,000,000, and correspond to 11 % of all cancers in patients aged 0–14 years....

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Bibliographic Details
Main Authors: Daniel Orbach, Ines B. Brecht, Nadege Corradini, Yassine Bouchoucha, Jelena Roganovic, Franck Bourdeaut, Yves Reguerre, Roland P. Kuiper, Brigitte Bressac de Paillerets, Andrea Ferrari, Calogero Virgone, Jan Godzinski, Gianni Bisogno, Lea Guerrini-Rousseau, Nuno Jorge Farinha, Luca Bergamaschi, Ewa Bien, Michaela Kuhlen, Dominik T. Schneider, Tal Ben Ami
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:EJC Paediatric Oncology
Subjects:
Paediatric/adolescent oncology
Very rare tumours
Genetic predisposition
Online Access:http://www.sciencedirect.com/science/article/pii/S2772610X23000211

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http://www.sciencedirect.com/science/article/pii/S2772610X23000211

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