Vascular Leak and Hypercytokinemia Associated with Severe Fever with Thrombocytopenia Syndrome Virus Infection in Mice

Vascular Leak and Hypercytokinemia Associated with Severe Fever with Thrombocytopenia Syndrome Virus Infection in Mice

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging viral hemorrhagic fever (VHF) endemic to China, South Korea, Japan, and Vietnam. Here we characterize the pathogenesis and natural history of disease in IFNAR<sup>-/-</sup> mice challenged with the HB29 strain of SFTS viru...

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Bibliographic Details
Main Authors: Jonna B. Westover, Brady T. Hickerson, Arnaud J. Van Wettere, Brett L. Hurst, Jacqueline P. Kurz, Ashley Dagley, Petra Wülfroth, Takashi Komeno, Yousuke Furuta, Thomas Steiner, Brian B. Gowen
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Pathogens
Subjects:
severe fever with thrombocytopenia syndrome
Huaiyangshan banyangvirus
viral hemorrhagic fever
vascular leak
cytokine storm
Online Access:https://www.mdpi.com/2076-0817/8/4/158

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https://www.mdpi.com/2076-0817/8/4/158

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