Protection against Congenital CMV Infection Conferred by MVA-Vectored Subunit Vaccines Extends to a Second Pregnancy after Maternal Challenge with a Heterologous, Novel Strain Variant

Protection against Congenital CMV Infection Conferred by MVA-Vectored Subunit Vaccines Extends to a Second Pregnancy after Maternal Challenge with a Heterologous, Novel Strain Variant

Maternal reinfection of immune women with novel human cytomegalovirus (HCMV) strains acquired during pregnancy can result in symptomatic congenital CMV (cCMV) infection. Novel animal model strategies are needed to explore vaccine-mediated protections against maternal reinfection. To investigate this...

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Bibliographic Details
Main Authors: Claudia Fernández-Alarcón, Grace Buchholz, Heidi Contreras, Felix Wussow, Jenny Nguyen, Don J. Diamond, Mark R. Schleiss
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Viruses
Subjects:
CMV vaccine
CMV reinfection
CIDTMR strain
TAMYC
pentameric complex
gO
Online Access:https://www.mdpi.com/1999-4915/13/12/2551

Internet

https://www.mdpi.com/1999-4915/13/12/2551

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