Investigating the Diversity of Tuberculosis Spoligotypes with Dimensionality Reduction and Graph Theory

The spoligotype is a graphical description of the CRISPR locus present in <i>Mycobacterium tuberculosis</i>, which has the particularity of having only 68 possible spacers. This spoligotype, which can be easily obtained either in vitro or in silico, allows to have a summary information o...

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Bibliographic Details
Main Authors: Gaetan Senelle, Christophe Guyeux, Guislaine Refrégier, Christophe Sola
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/13/12/2328