CRISPR DNA Base Editing Strategies for Treating Retinitis Pigmentosa Caused by Mutations in <i>Rhodopsin</i>

Retinitis pigmentosa (RP) is the most common group of inherited retinal degenerations and pathogenic variants in the <i>Rhodopsin</i> (<i>RHO</i>) gene are major cause for autosomal dominant RP (adRP). Despite extensive attempts to treat <i>RHO</i>-associated adRP...

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Bibliographic Details
Main Authors: Maria Kaukonen, Michelle E. McClements, Robert E. MacLaren
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/13/8/1327