Metabotropic Glutamate Receptors for Parkinson's Disease Therapy

Excessive glutamatergic signalling within the basal ganglia is implicated in the progression of Parkinson’s disease (PD) and inthe emergence of dyskinesia associated with long-term treatment with L-DOPA. There is considerable research focus on the discovery and development of compounds that modulate...

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Detalles Bibliográficos
Main Authors: Fabrizio Gasparini, Thérèse Di Paolo, Baltazar Gomez-Mancilla
Formato: Artigo
Idioma:English
Publicado: Wiley 2013-01-01
Series:Parkinson's Disease
Acceso en liña:http://dx.doi.org/10.1155/2013/196028