Pharmacological targets for the induction of ferroptosis: Focus on Neuroblastoma and Glioblastoma

Pharmacological targets for the induction of ferroptosis: Focus on Neuroblastoma and Glioblastoma

Neuroblastomas are the main extracranial tumors that affect children, while glioblastomas are the most lethal brain tumors, with a median survival time of less than 12 months, and the prognosis of these tumors is poor due to multidrug resistance. Thus, the development of new therapies for the treatm...

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Bibliographic Details
Main Authors: Luciano Ferrada, María José Barahona, Katterine Salazar, Alejandro S. Godoy, Matias Vera, Francisco Nualart
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
ferroptosis
cancer cell
brain tumors
GPX4
system xc−
lipid ROS
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.858480/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.858480/full

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