MTHFD2 is a potential oncogene for its strong association with poor prognosis and high level of immune infiltrates in urothelial carcinomas of bladder

Abstract Background The bifunctional methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (MTHFD2) has been reported to play an oncogenic role in various types of cancers. However, the function of MTHFD2 in urothelial carcinomas of bladder (UCB) and it...

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Bibliographic Details
Main Authors: Lin Zhu, Xianhui Liu, Weiyu Zhang, Hao Hu, Qi Wang, Kexin Xu
Format: Article
Language:English
Published: BMC 2022-05-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-022-09606-0