Systematic engineering of branch chain amino acid supply modules for the enhanced production of bacitracin from Bacillus licheniformis
Bacitracin is a broad-spectrum cyclic peptide antibiotic mainly produced by Bacillus, precursor amino acid supply served as the critical role during its synthesis. In this study, we systematically engineered branch-chain amino acid (BCAA) supply modules for bacitracin production. Firstly, we demonst...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-12-01
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Series: | Metabolic Engineering Communications |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2214030120300092 |