A multidimensional atlas of human glioblastoma-like organoids reveals highly coordinated molecular networks and effective drugs

A multidimensional atlas of human glioblastoma-like organoids reveals highly coordinated molecular networks and effective drugs

Abstract Recent advances in the genomics of glioblastoma (GBM) led to the introduction of molecular neuropathology but failed to translate into treatment improvement. This is largely attributed to the genetic and phenotypic heterogeneity of GBM, which are considered the major obstacle to GBM therapy...

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Bibliographic Details
Main Authors: Changwen Wang, Meng Sun, Chunxuan Shao, Lisa Schlicker, Yue Zhuo, Yassin Harim, Tianping Peng, Weili Tian, Nadja Stöffler, Martin Schneider, Dominic Helm, Youjun Chu, Beibei Fu, Xiaoliang Jin, Jan-Philipp Mallm, Moritz Mall, Yonghe Wu, Almut Schulze, Hai-Kun Liu
Format: Article
Language:English
Published: Nature Portfolio 2024-01-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-024-00500-5

Internet

https://doi.org/10.1038/s41698-024-00500-5

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