Formyl Peptide Receptor 2 Alleviates Hepatic Fibrosis in Liver Cirrhosis by Vascular Remodeling

Formyl Peptide Receptor 2 Alleviates Hepatic Fibrosis in Liver Cirrhosis by Vascular Remodeling

Hexapeptide WKYMVm (Trp-Lys-Tyr-Met-Val-D-Met), a ligand of formyl peptide receptor 2, exhibits anti-inflammatory and angiogenic properties in disease models. However, the therapeutic effects of WKYMVm on hepatic fibrosis have not been evaluated to date. Therefore, we investigated whether WKYMVm exe...

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Bibliographic Details
Main Authors: Ji Hye Jun, Soo Young Park, Sohae Park, Hee Jung Park, Jae Yeon Kim, Gyu Tae Park, Si Hyun Bae, Jae Ho Kim, Gi Jin Kim
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
liver cirrhosis
WKYMVm
angiogenesis
fibrosis
regeneration
Online Access:https://www.mdpi.com/1422-0067/22/4/2107

Internet

https://www.mdpi.com/1422-0067/22/4/2107

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