2-[3-(Aziridin-1-yl)-2-hydroxypropyl]-5,5-dimethyl-2,5-dihydro-4H-benzo[e]isoindol-4-one (Cytotoxic Oxonaphthalene-Pyrroles, Part III)

An hydroxypropyl-aziridine-containing side chain is attached to an oxonaphthalene-annelated pyrrole in expectation of DNA alkylating properties. The cytotoxicity is evaluated against two cell lines, KB-31 and KB-8511, respectively.

Bibliographic Details
Main Authors: Christiane Puschmann, Helmut Spreitzer
Format: Article
Language:English
Published: MDPI AG 2012-08-01
Series:Molbank
Subjects:
Online Access:http://www.mdpi.com/1422-8599/2012/3/M772