2-[3-(Aziridin-1-yl)-2-hydroxypropyl]-5,5-dimethyl-2,5-dihydro-4H-benzo[e]isoindol-4-one (Cytotoxic Oxonaphthalene-Pyrroles, Part III)
An hydroxypropyl-aziridine-containing side chain is attached to an oxonaphthalene-annelated pyrrole in expectation of DNA alkylating properties. The cytotoxicity is evaluated against two cell lines, KB-31 and KB-8511, respectively.
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2012-08-01
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Series: | Molbank |
Subjects: | |
Online Access: | http://www.mdpi.com/1422-8599/2012/3/M772 |