Evaluation of Anti-Neuroinflammatory Activity of Isatin Derivatives in Activated Microglia

Evaluation of Anti-Neuroinflammatory Activity of Isatin Derivatives in Activated Microglia

Neuroinflammation plays a crucial role in the progression of Alzheimer’s disease and other neurodegenerative disorders. Overactivated microglia cause neurotoxicity and prolong the inflammatory response in many neuropathologies. In this study, we have synthesised a series of isatin derivatives to eva...

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Bibliographic Details
Main Authors: Alejandro Cenalmor, Elena Pascual, Sergio Gil-Manso, Rafael Correa-Rocha, José Ramón Suárez, Isabel García-Álvarez
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Molecules
Subjects:
neuroinflammation
microglia
isatin
nitric oxide
interleukin 6
TNF-α
Online Access:https://www.mdpi.com/1420-3049/28/12/4882

Internet

https://www.mdpi.com/1420-3049/28/12/4882

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