Exogenous Melatonin in the Culture Medium Does Not Affect the Development of In Vivo-Derived Pig Embryos but Substantially Improves the Quality of In Vitro-Produced Embryos

Exogenous Melatonin in the Culture Medium Does Not Affect the Development of In Vivo-Derived Pig Embryos but Substantially Improves the Quality of In Vitro-Produced Embryos

Cloned and transgenic pigs are relevant human disease models and serve as potential donors for regenerative medicine and xenotransplantation. These technologies demand oocytes and embryos of good quality. However, the current protocols for in vitro production (IVP) of pig embryos give reduced blasto...

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Bibliographic Details
Main Authors: Cristina A. Martinez, Cristina Cuello, Inmaculada Parrilla, Carolina Maside, Guillermo Ramis, Josep M. Cambra, Juan M. Vazquez, Heriberto Rodriguez-Martinez, Maria A. Gil, Emilio A. Martinez
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Antioxidants
Subjects:
melatonin
in vitro fertilization
reactive oxygen species
in vivo-derived embryos
CRISPR/Cas9
apoptosis
Online Access:https://www.mdpi.com/2076-3921/11/6/1177

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https://www.mdpi.com/2076-3921/11/6/1177

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