Coxiella burnetii Affects HIF1α Accumulation and HIF1α Target Gene Expression

Coxiella burnetii Affects HIF1α Accumulation and HIF1α Target Gene Expression

HIF1α is an important transcription factor regulating not only cellular responses to hypoxia, but also anti-infective defense responses. We recently showed that HIF1α hampers replication of the obligate intracellular pathogen Coxiella burnetii which causes the zoonotic disease Q fever. Prior to deve...

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Bibliographic Details
Main Authors: Inaya Hayek, Manuela Szperlinski, Anja Lührmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Coxiella burnetii
HIF1α
T4SS
metabolism
apoptosis
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.867689/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2022.867689/full

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