Pathology of Gastrointestinal Stromal Tumors

Gastrointestinal stromal tumor (GIST) is a well recognized and relatively well understood soft tissue tumor. Early events in GIST development are activating mutations in KIT or PDGFRA , which occur in most GISTs and encode for mutated tyrosine receptor kinases that are therapeutic targets for tyrosi...

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Bibliographic Details
Main Authors: Wai Chin Foo, Bernadette Liegl-Atzwanger, Alexander J. Lazar
Format: Article
Language:English
Published: SAGE Publishing 2012-01-01
Series:Clinical Medicine Insights: Pathology
Online Access:https://doi.org/10.4137/CPath.S9689