Increased cardiac Pi/PCr in the diabetic heart observed using phosphorus magnetic resonance spectroscopy at 7T

Phosphorus magnetic resonance spectroscopy (31P-MRS) has previously demonstrated decreased energy reserves in the form of phosphocreatine to adenosine-tri-phosphate ratio (PCr/ATP) in the hearts of patients with type 2 diabetes (T2DM). Recent 31P-MRS techniques using 7T systems, e.g. long mixing tim...

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Bibliographic Details
Main Authors: Ladislav Valkovič, Andrew Apps, Jane Ellis, Stefan Neubauer, Damian J. Tyler, Albrecht Ingo Schmid, Oliver J. Rider, Christopher T. Rodgers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202907/?tool=EBI