Pain and Cellular Migration Induced by Bothrops jararaca Venom in Mice Selected for an Acute Inflammatory Response: Involvement of Mast Cells

Bothrops jararaca venom (BjV) can induce mast cell degranulation. In order to investigate the role of mast cells and the interference of the host genetic background in the inflammation induced by BjV, we have used mouse strains selected for maximal (AIRmax) or minimal (AIRmin) acute inflammatory res...

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Main Authors: Fernanda V. Kondo, Wafa H. K. Cabrera, Orlando G. Ribeiro, Marcelo De Franco, José Ricardo Jensen, Gisele Picolo, Morena B. Sant’Anna, Monica Spadafora-Ferreira, Andrea Borrego, Olga M. Ibañez, Nancy Starobinas
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.779473/full