Epigenetic telomere protection by Drosophila DNA damage response pathways.

Analysis of terminal deletion chromosomes indicates that a sequence-independent mechanism regulates protection of Drosophila telomeres. Mutations in Drosophila DNA damage response genes such as atm/tefu, mre11, or rad50 disrupt telomere protection and localization of the telomere-associated proteins...

Full description

Bibliographic Details
Main Authors: Sarah R Oikemus, Joana Queiroz-Machado, KuanJu Lai, Nadine McGinnis, Claudio Sunkel, Michael H Brodsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-05-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1463044?pdf=render