Physiologically Based Pharmacokinetic (PBPK) Model of Gold Nanoparticle-Based Drug Delivery System for Stavudine Biodistribution

Physiologically Based Pharmacokinetic (PBPK) Model of Gold Nanoparticle-Based Drug Delivery System for Stavudine Biodistribution

Computational modelling has gained attention for evaluating nanoparticle-based drug delivery systems. Physiologically based pharmacokinetic (PBPK) modelling provides a mechanistic approach for evaluating drug biodistribution. The aim of this work is to develop a specific PBPK model to simulate stavu...

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Bibliographic Details
Main Authors: Hinojal Zazo, Clara I. Colino, Carmen Gutiérrez-Millán, Andres A. Cordero, Matthias Bartneck, José M. Lanao
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Pharmaceutics
Subjects:
gold nanoparticles
stavudine
pharmacokinetics
biodistribution
PBPK model
Online Access:https://www.mdpi.com/1999-4923/14/2/406

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https://www.mdpi.com/1999-4923/14/2/406

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