Ghrelin inhibits the differentiation of T helper 17 cells through mTOR/STAT3 signaling pathway.

Enhanced activity of interleukin 17 (IL-17) producing T helper 17 (Th17) cells plays an important role in autoimmune and inflammatory diseases. Significant loss of body weight and appetite is associated with chronic inflammation and immune activation, suggesting the cross talk between immune and neu...

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Bibliographic Details
Main Authors: Yanhui Xu, Ziru Li, Yue Yin, He Lan, Jun Wang, Jing Zhao, Juan Feng, Yin Li, Weizhen Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4319964?pdf=render