Efficacy and safety of sodium-glucose cotransporter-2 inhibitors for heart failure with mildly reduced or preserved ejection fraction: a systematic review and meta-analysis of randomized controlled trials

AimsWe sought to conduct a meta-analysis to evaluate the efficacy and safety of sodium-glucose cotransporter-2 inhibitors (SGLT2i) in patients with heart failure (HF) with preserved ejection fraction (HFpEF) and HF with mildly reduced ejection fraction (HFmrEF).MethodsWe searched the Cochrane Librar...

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Main Authors: Huzaifa Ahmad Cheema, Arman Shafiee, Mohammad Mobin Teymouri Athar, Mohammad Ali Rafiei, Atefe Mehmannavaz, Kyana Jafarabady, Abia Shahid, Adeel Ahmad, Sardar Hassan Ijaz, Sourbha S. Dani, Abdul Mannan Khan Minhas, Abdulqadir J. Nashwan, Marat Fudim, Gregg C. Fonarow
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1273781/full