Association between common polymorphism near the MC4R gene and obesity risk: a systematic review and meta-analysis.

BACKGROUND: Genome-wide association studies on Europeans have shown that two polymorphisms (rs17782313, rs12970134) near the melanocortin 4 receptor (MC4R) gene were associated with increased risk of obesity. Subsequently studies among different ethnic populations have shown mixed results with some...

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Bibliographic Details
Main Authors: Bo Xi, Giriraj R Chandak, Yue Shen, Qijuan Wang, Donghao Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3458070?pdf=render