Intra and Extra-granular Disintegrant Properties of Modified Underutilised Red Lima Bean Starch in Paracetamol Tablet Formulation

Intra and Extra-granular Disintegrant Properties of Modified Underutilised Red Lima Bean Starch in Paracetamol Tablet Formulation

Abstract Red lima bean (Phaseolus lunatus Linn) Family Fabaceae, has been modified by succinylation and annealing, and used as intra- and extra-granular disintegrants at concentrations of 5 and 10 %w/w in paracetamol tablet formulation in comparison with corn starch BP. The starches were characteris...

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Bibliographic Details
Main Authors: Mary Oluwaseun Okekunle, Olufunke Dorothy Akin-Ajani, Bridget Lucy Ekpukpon, Oluwatoyin Adepeju Odeku, Bamidele Iromidayo Olu-Owolabi, Kayode Oyebode Adebowale
Format: Article
Language:English
Published: Universidade de São Paulo 2022-07-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Red lima bean
Succinylation
Annealed
Intra and extra-granular Disintegrants
Modified starches
Underutilised
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502022000100651&lng=en&tlng=en

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