Determination of critical concentration for drug susceptibility testing of Mycobacterium tuberculosis against para-aminosalicylic acid with clinical isolates with thyA, folC and dfrA mutations

Determination of critical concentration for drug susceptibility testing of Mycobacterium tuberculosis against para-aminosalicylic acid with clinical isolates with thyA, folC and dfrA mutations

Abstract Background & Objectives Accurate determination of antimicrobial resistance profiles is of great importance to formulate optimal regimens against multidrug-resistant tuberculosis (MDR-TB). Although para-aminosalicylic acid (PAS) has been widely used clinically, the reliable testing metho...

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Bibliographic Details
Main Authors: Wei Wang, Shanshan Li, Qiping Ge, Haiping Guo, Yuanyuan Shang, Weicong Ren, Yufeng Wang, Zhongtan Xue, Jie Lu, Yu Pang
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Annals of Clinical Microbiology and Antimicrobials
Subjects:
Mycobacterium tuberculosis
Para-Aminosalicylic Acid
Critical Concentration
Drug Susceptibility Testing
Online Access:https://doi.org/10.1186/s12941-022-00537-z

Internet

https://doi.org/10.1186/s12941-022-00537-z

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