Orally disintegrating tablet: formulation design and optimisation using Response Surface Methodology

The objective of this study was to develop diazepam orally disintegrating tablets and to optimize tablets characteristics using response surface methodology (RSM). Tablets were prepared by direct compression of mixture containing mannitol, copovidone, crosspovidone flavor and lubricant. A full fac...

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Bibliographic Details
Main Authors: Biljana Nestorovska-Gjosevska, Marija Glavas-Dodov, Katerina Goracinova
Format: Article
Language:English
Published: University Ss Cyril and Methodius in Skopje, Faculty of Pharmacy and Macedonian Pharmaceutical Association 2005-12-01
Series:Makedonsko Farmacevtski Bilten
Online Access:http://bulletin.mfd.org.mk/volumes/Volume%2051/51_003.pdf